Drug intelligence / Profile preview

somatropin + folic acid

Development stage: Unknown
Lead developer: Beni-Suef University
Modality: Recombinant Proteins and Enzymes, Small Molecules
Administration: Subcutaneous, Oral

Overview

Somatropin + folic acid is a combination therapy being investigated by Beni-Suef University for the treatment of infertility in women with poor ovarian reserve (POR) undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). Somatropin, a recombinant human growth hormone, is hypothesized to enhance ovarian response and oocyte quality by stimulating the production of insulin-like growth factor 1 (IGF-1) and modulating gonadotropin action. Folic acid is included as a standard prenatal supplement to support DNA synthesis and prevent neural tube defects. This specific combination is being evaluated in clinical trials to determine if growth hormone supplementation can improve the number and size of follicles and overall pregnancy outcomes in patients who typically respond poorly to standard ovarian stimulation protocols.

Other names: growth hormone + folic acid

Targets

FOLR1 (FRα)GHR (Growth hormone receptor)FOLR2 (Folate receptor beta)

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