SophorOx

SophorOx is a proprietary polyphenol-rich antioxidant blend derived from the buds of *Sophora japonica* L (also known as *Styphnolobium japonicum*), standardized to contain at least 90% flavonoids. Its primary active components are quercetin and rutin. Developed as a natural supplement, it is designed to reduce oxidative stress and inflammation in overweight or obese individuals. Mechanistically, it acts by inhibiting pro-inflammatory cytokines such as TNF-α and IL-6 and reducing markers of oxidative stress including malondialdehyde (MDA), 8-isoprostane (8-iso-PGF2α), and 8-hydroxydeoxyguanosine (8-OHdG). Human clinical studies have shown that supplementation with SophorOx leads to significant reductions in oxidative stress biomarkers, improvements in body composition metrics such as weight and waist circumference, and enhanced quality of life measures. Preclinical studies further support its anti-inflammatory effects without notable adverse events[1][2][5][7].

Brand names

SophorOxSophorOx™SophorOx®

Other names

quercetin–rutin blendstandardized sophora japonica extract