Drug intelligence / Profile preview

SOR007

Development stage
Phase 2
Lead developer
NanOlogy
Modality
Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

SOR007 is a sterile nanoparticulate paclitaxel formulation administered topically for the treatment of various cancers. It is developed using supercritical precipitation (SCP) technology, which creates submicron particles that can penetrate the skin with minimal systemic absorption. The drug works through paclitaxel's cytotoxic mechanism of action, providing a continuous dose to diseased skin over time with limited systemic exposure. SOR007 has shown promising results in clinical trials for treating cutaneous metastases of breast cancer, with better response rates observed with longer treatment duration (56 days vs 28 days).

Other names
Topical submicron particle paclitaxelUncoated Nanoparticle Paclitaxel Ointment
02

Targets

TUBB (Tubulin (alpha and beta subunits))

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