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soufeng sanjie formula
- Development stage
- Preclinical
- Lead developer
- Jiangsu Province Hospital on Integration of Chinese and Western Medicine
- Administration
- Oral
01
Overview
Soufeng Sanjie formula is a Traditional Chinese Medicine (TCM) preparation developed by the Jiangsu Integrated Traditional Chinese and Western Medicine Hospital for the treatment of advanced rheumatoid arthritis (RA). It is specifically indicated for patients presenting with 'Phlegm-stasis bi syndrome' (痰瘀痹阻证), a TCM classification characterized by chronic joint pain, swelling, and deformity. The formula utilizes 'insecticidal' or 'wind-searching' medicinal components (chonglei yao) intended to penetrate deep into the meridians to resolve phlegm and dissipate blood stasis. Clinical research focuses on its potential to inhibit bone erosion and joint destruction, aiming to provide a scientific basis for the use of traditional insect-based drugs in managing RA progression.
- Other names
- Soufeng Sanjie formulaSoufeng Sanjie fomula
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)STAT3 (Signal Transducer and Activator of Transcription 3)RANKL (Receptor activator of nuclear factor kappa-B ligand)
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