Drug intelligence / Profile preview

sour diesel

Development stage
Unknown
Modality
Small Molecules
Administration
Inhalation, Oral
01

Overview

Sour Diesel, also known as Sour D, is a prominent sativa-dominant hybrid cannabis strain recognized for its pungent, diesel-like aromatic profile and its energizing, cerebral effects. Originating in the early 1990s, its lineage is generally attributed to a cross between Chemdawg 91 and Super Skunk. Pharmacologically, Sour Diesel exerts its effects primarily through its high concentration of delta-9-tetrahydrocannabinol (THC), which functions as a partial agonist at the cannabinoid type 1 (CB1) and type 2 (CB2) receptors. The activation of CB1 receptors in the central nervous system is responsible for the strain's psychoactive properties and its use in managing symptoms of depression and fatigue, while CB2 receptor interaction contributes to its potential anti-inflammatory and analgesic applications. Additionally, the strain contains a complex profile of terpenes, including caryophyllene, limonene, and myrcene, which may modulate the activity of cannabinoids through the entourage effect. While not an FDA-approved pharmaceutical, Sour Diesel is widely utilized within legal medical cannabis frameworks for the treatment of chronic pain, stress, and mood disorders.

Brand names
Sour DieselSour D
Other names
Sour DEast Coast Sour Diesel
02

Targets

CNR1 (Cannabinoid receptor 1)

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