soybean oil (Assistance Publique-Hôpitaux de Marseille)

Endolipide is an intravenous lipid emulsion, typically containing 20% soybean oil, used primarily as a source of energy and essential fatty acids in parenteral nutrition. In the context of clinical research, specifically a Phase 3 academic study conducted by Assistance Publique - Hôpitaux de Marseille (NCT01083472), Endolipide is utilized as a standardized lipid challenge to investigate metabolic regulation. The study evaluates the acute effects of intensive insulin therapy on the production and metabolism of intestinal triglyceride-rich lipoproteins (TRLs) in adults with type 2 diabetes mellitus. By administering Endolipide, researchers can maintain stable plasma lipid levels (a "lipid clamp") to observe how insulin modulates the assembly and secretion of chylomicrons and other lipoproteins, providing insights into the pathophysiology of diabetic dyslipidemia.

Brand names

EndolipideIntralipidLipofundin

Other names

Endolipide 20%lipid emulsionsoybean oil emulsionfat emulsion