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soybean phytosterol
- Development stage
- Phase 2
- Lead developer
- Conba Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Soybean phytosterol is a botanical extract derived from soybeans, primarily consisting of a mixture of plant sterols such as beta-sitosterol, campesterol, and stigmasterol. It is being developed as a pharmaceutical product, notably under the brand name Pureixiao, for the treatment of chronic nonbacterial prostatitis (NIH category III). The therapeutic effect is attributed to its anti-inflammatory properties and its ability to inhibit 5-alpha-reductase, thereby reducing the production of dihydrotestosterone (DHT) and alleviating symptoms of prostatic congestion and inflammation. Clinical evaluation in China has focused on its efficacy in improving voiding symptoms and reducing pelvic pain in men with chronic prostatitis.
- Brand names
- Pureixiao
- Other names
- soybean sterolsphytosterolssoybean-derived phytosterols
02
Targets
SRD5A1 (Steroid 5-alpha-reductase type 1)SRD5A2 (Steroid 5-alpha-reductase type II)NPC1L1 (Niemann-Pick C1-like 1)SRD5A (Steroid 5-alpha-reductase)
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