Drug intelligence / Profile preview

spearmint extract + alpha-glyceryl phosphoryl choline + phosphatidylserine + pyrroloquinoline quinone

Development stage
Unknown
Lead developer
LifeExtension
Modality
Small Molecules
Administration
Oral
01

Overview

Spearmint extract + alpha-glyceryl phosphoryl choline + phosphatidylserine + pyrroloquinoline quinone is a multi-ingredient nootropic combination designed to support cognitive function, memory, and neuroprotection. This specific stack leverages the synergistic effects of four distinct compounds: **spearmint extract** (often standardized to rosmarinic acid, such as Neumentix), which provides antioxidant support and inhibits acetylcholinesterase; **alpha-glyceryl phosphoryl choline (Alpha-GPC)**, a highly bioavailable choline donor that increases brain acetylcholine levels; **phosphatidylserine (PS)**, a critical phospholipid for maintaining neuronal membrane integrity and facilitating cell-to-cell communication; and **pyrroloquinoline quinone (PQQ)**, a redox cofactor that stimulates mitochondrial biogenesis via the PGC-1alpha pathway. The combination is primarily marketed as a dietary supplement to address age-related cognitive decline, enhance focus, and support long-term brain health.

Brand names
Cognitex Elite PQQ
Other names
Neumentix + Alpha-GPC + PS + PQQspearmint extract + alpha-GPC + phosphatidylserine + PQQ
02

Targets

AcetylcholinesterasePPARGC1A (Peroxisome proliferator–activated receptor gamma coactivator 1-alpha)HSPA8 (Heat shock cognate 71 kDa protein)

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