spherical carbon adsorbent

DW-7202 (Renamezin) is an oral spherical carbon adsorbent developed by Daewon Pharmaceutical and PureSphere. It consists of porous, black spherical carbon particles derived from a furan resin-based formulation, which provides high adsorptive selectivity for uremic toxins. DW-7202 is designed to delay the progression of chronic kidney disease (CKD) and alleviate uremic symptoms by physically adsorbing uremic toxins and their precursors (such as indoxyl sulfate and p-cresyl sulfate) in the gastrointestinal tract. This prevents their absorption into the systemic circulation and promotes their excretion in feces. It is approved in South Korea and Taiwan as a capsule formulation, offering improved patient adherence and tolerability compared to traditional granule-type carbon adsorbents like AST-120.

Brand names

RenaMezinRenemezin

Other names

spherical adsorptive carbonspherical carbonaceous adsorbent