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Spinacia oleracea aqueous extract (AESO) is a botanical research compound derived from the leaves of common spinach (Spinacia oleracea). It is a complex natural mixture containing active phytochemicals such as flavonoids and tannins. Preclinical research has investigated its potential in treating inflammatory bowel disease (colitis, enterocolitis), asthma, psoriasis, and central nervous system disorders like seizures. Its proposed mechanisms of action include anti-inflammatory activity through the reduction of IL-4 and IL-13 cytokines, antioxidant effects, and the modulation of monoamine neurotransmitters such as serotonin, norepinephrine, and dopamine. Currently, there are no known commercial developers or clinical trials associated with this extract, and it remains in the preclinical stage of investigation.
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