spongosine

**Spongosine** (2-methoxyadenosine, CAS 24723-77-1) is a naturally occurring purine nucleoside analog isolated from marine sponges, particularly the Tethyidae family and Cryptotethya crypta. It functions as an antagonist of adenosine receptors (A1, A2A, A3), exhibiting diverse bioactivities including anti-inflammatory effects, analgesic properties, and vasodilation. As a research compound, it has shown potential antitumor activity against indolent lymphoid malignancies typical of purine nucleoside analogs, though it remains preclinical without approved indications.[1][3][7][9]

Other names

2-methoxyadenosine2-methoxy adenosine