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Spur Therapeutics (formerly Freeline Therapeutics) is developing an unnamed, research-stage gene therapy program for the treatment of severe chronic heart failure. The approach involves the delivery of genes encoding a suite of cardioprotective proteins designed to improve cardiac function and arrest the progression of heart failure. This program marks the company's strategic expansion from rare monogenic diseases into more common, prevalent chronic conditions. As of 2024, a specific lead candidate has not been publicly named, and the program remains in the research phase.
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