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SQJZ is a traditional Chinese medicine (TCM) herbal mixture developed by Dongzhimen Hospital, Beijing, for the treatment of non-motor symptoms (NMS) in Parkinson's disease. The formula is composed of several Chinese herb extracts, including *Rehmannia glutinosa* Libosch and *Astragalus membranaceus* (Fisch.) Bunge. It is specifically designed to address a range of NMS such as insomnia, constipation, and anxiety, which are common in Parkinson's patients. The mixture is currently being evaluated in multicenter, randomized, double-blind, placebo-controlled Phase 2 clinical trials to assess its efficacy and safety, with primary outcomes measured using the Non-Motor Symptom Scale (NMSS).
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