Drug intelligence / Profile preview

squalene

Development stage
Unknown
Modality
Small Molecules
Administration
Intramuscular, Oral, Topical, Subcutaneous
01

Overview

Squalene is a natural 30-carbon isoprenoid compound and triterpene with the formula C₃₀H₅₀. It was originally obtained from shark liver oil but is also found in plants, fungi, and produced endogenously in humans as an intermediate metabolite in cholesterol synthesis. Squalene is used as a moisturizing agent in cosmetics due to its similarity to natural skin oils, providing hydration and protection against irritation. In pharmaceuticals, it serves as an adjuvant in vaccines (e.g., influenza vaccines), enhancing immune response by facilitating antigen presentation to immune cells such as macrophages and dendritic cells. Squalene has antioxidant properties and may contribute to cardiovascular health by improving lipid profiles[2][3][4].

Other names
SpinaceneSupraene
02

Targets

Biological membrane

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