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Sravathi AI Pancreatic Cancer PROTAC

Development stage
Preclinical
Lead developer
Sravathi AI Technology
Modality
PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
01

Overview

Sravathi AI Technology is developing a proteolysis-targeting chimera (PROTAC) for the treatment of pancreatic cancer. This therapeutic candidate is designed to utilize the cell's natural protein degradation machinery by recruiting an E3 ubiquitin ligase to a specific, though currently undisclosed, target protein. By facilitating the ubiquitination and subsequent proteasomal degradation of the target, the drug aims to inhibit oncogenic signaling pathways relevant to pancreatic cancer progression. As of early 2024, the program is in the Lead Identification (Lead ID) stage of preclinical discovery.

Other names
Protac

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