Drug intelligence / Profile preview

SRL172 + mitomycin + vinblastine + cisplatin

Development stage
Unknown
Lead developer
SRL
Modality
Small Molecules, Vaccines & Immunotherapeutics
Administration
Intradermal, Intravenous
01

Overview

SRL172 is a heat-killed preparation of Mycobacterium vaccae used as an immunotherapeutic agent in cancer treatment. Mitomycin, vinblastine, and cisplatin are chemotherapeutic agents commonly combined in regimens such as MVP (mitomycin-vinblastine-cisplatin or carboplatin). The regimen "SRL172 + mitomycin + vinblastine + cisplatin" has been studied in clinical trials for advanced non-small cell lung cancer (NSCLC) and mesothelioma. The mechanism of action involves both immune stimulation by SRL172 and cytotoxic effects from the chemotherapy agents[1][2]. Clinical studies suggest that adding SRL172 to chemotherapy may improve quality of life and possibly response rates without significantly affecting overall survival[2].

02

Targets

TUBB (Tubulin (alpha and beta subunits))DNAPRR (Pattern recognition receptors)

Beyond the preview

Go deeper on SRL172 + mitomycin + vinblastine + cisplatin.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on SRL172 + mitomycin + vinblastine + cisplatin.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call