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SRNDC-01
- Development stage
- Preclinical
- Lead developer
- Sirius Therapeutics
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
SRNDC-01 is an investigational small interfering RNA (siRNA) therapy being developed by Sirius Therapeutics (also known as Sirius Natural) for the treatment of coagulation disorders. The drug is designed to produce an anticoagulant effect through siRNA-mediated gene silencing of a specific, currently undisclosed, target within the coagulation cascade. SRNDC-01 utilizes the company's proprietary delivery platforms, which are engineered for targeted delivery to various tissues, including the liver, adipose tissue, heart, kidney, or the central nervous system (CNS). It is currently in the pre-clinical and IND-enabling stage of development.
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