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SRNDC-02
- Development stage
- Preclinical
- Lead developer
- Sirius Therapeutics
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
SRNDC-02 is an investigational small interfering RNA (siRNA) therapy being developed by Sirius Therapeutics (formerly Sirius Natural) for the treatment of coagulation disorders. It is designed to produce an anticoagulant effect by utilizing siRNA-mediated gene silencing to reduce the expression of an undisclosed protein target involved in the blood clotting cascade. The therapy leverages the company's proprietary delivery platforms, which are capable of targeting tissues such as the liver, adipose, heart, kidney, or central nervous system (CNS). SRNDC-02 is currently in the preclinical/IND-enabling stage of development.
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