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SRNDM-03

Development stage: Preclinical
Lead developer: Sirius Therapeutics
Modality: Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics

Overview

SRNDM-03 is an investigational small interfering RNA (siRNA) therapeutic candidate being developed by Sirius Therapeutics (formerly Sirius Natural) for the treatment of cardiometabolic diseases. As part of Sirius's proprietary RNA interference (RNAi) platform, SRNDM-03 is designed to achieve targeted gene silencing of an undisclosed molecular target. The company's delivery technology is engineered to reach various tissues, including the liver, adipose tissue, heart, kidneys, and the central nervous system (CNS), to optimize the therapeutic profile of its assets. SRNDM-03 is currently in the pre-clinical stage of development, progressing toward an Investigational New Drug (IND) application.

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