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SRNDM-06

Development stage: Preclinical
Lead developer: Sirius Therapeutics
Modality: Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics

Overview

SRNDM-06 is an investigational small interfering RNA (siRNA) therapy being developed by Sirius Therapeutics for the treatment of heart failure. As part of the company's cardiometabolic pipeline, SRNDM-06 utilizes siRNA-mediated gene silencing to modulate a specific, currently undisclosed molecular target associated with heart failure pathology. The drug is designed to be delivered using Sirius's proprietary delivery platforms, which are capable of targeting tissues including the liver, adipose, heart, kidney, or central nervous system. It is currently in the pre-clinical/IND-enabling stage of development.

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