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SRNDM-07

Development stage: Preclinical
Lead developer: Sirius Therapeutics
Modality: Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration: Subcutaneous

Overview

SRNDM-07 is an investigational small interfering RNA (siRNA) therapy being developed by Sirius Therapeutics (also known as Sirius Natural) for the treatment of heart failure. As part of the company's cardiometabolic disease pipeline, SRNDM-07 utilizes siRNA-mediated gene silencing to target an undisclosed molecular pathway involved in the pathogenesis of heart failure. The program leverages Sirius's proprietary delivery technology, which is designed to enable targeted delivery to various tissues, including the liver, adipose, heart, kidney, and central nervous system. SRNDM-07 is currently in the pre-clinical/IND-enabling stage of development.

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