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SRNDO-04
- Development stage
- Preclinical
- Lead developer
- Sirius Therapeutics
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Subcutaneous
01
Overview
SRNDO-04 is an investigational small interfering RNA (siRNA) therapy being developed by Sirius Therapeutics (formerly or also known as Sirius Natural) for the treatment of obesity. The drug is part of a pipeline of siRNA candidates designed to utilize proprietary delivery technologies that target specific tissues, including the liver, adipose tissue, heart, kidney, and the central nervous system (CNS). SRNDO-04 functions through siRNA-mediated gene silencing to reduce the expression of a specific molecular target involved in metabolic regulation; however, the identity of this target is currently undisclosed by the developer. The program is presently in the preclinical and IND-enabling stage of development.
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