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SRNDO-05

Development stage: Preclinical
Lead developer: Sirius Therapeutics
Modality: Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics

Overview

SRNDO-05 is a preclinical small interfering RNA (siRNA) therapeutic candidate being developed by Sirius Therapeutics (also known as Sirius Natural) for the treatment of muscle wasting. As part of the company's cardiometabolic and obesity-focused pipeline, SRNDO-05 utilizes proprietary delivery technology designed to target specific tissues such as the liver, adipose tissue, heart, kidney, or the central nervous system (CNS). The specific molecular target of the siRNA is currently undisclosed by the developer. The program is positioned within the obesity therapeutic area of the company's pipeline and is currently in the Pre-Clinical/IND-enabling stage of development.

Targets

F11 (Coagulation Factor XI)

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