Drug intelligence / Profile preview

ssAAV2-GFP

Development stage
Unknown
Modality
Viral Vectors → Gene Addition/Replacement → Gene Therapies
Administration
Intraocular, Subretinal Injection, Intravitreous Injection, Intracameral Injection
01

Overview

ssAAV2-GFP is a single-stranded adeno-associated virus serotype 2 (AAV2) vector engineered to deliver the gene encoding Green Fluorescent Protein (GFP). AAV2 vectors are commonly used in gene therapy research due to their ability to efficiently transduce a wide range of cell types and maintain long-term transgene expression. GFP is a reporter protein that emits green fluorescence, making ssAAV2-GFP a valuable tool for studying gene transfer, expression patterns, and viral vector trafficking in various biological systems, particularly in ocular gene therapy studies. It is not typically used as a therapeutic agent itself, as GFP does not exert a direct therapeutic effect.

02

Targets

HSPG (Basement membrane-specific heparan sulfate proteoglycan core protein (perlecan))

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