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SSR97225 is a small molecule tubulin-binding agent that acts as a tubulin inhibitor. It was developed by Sanofi for the treatment of solid tumors and refractory cancers. The drug works by binding to tubulin, arresting the cell cycle at the G2/M checkpoint, and preventing mitosis, thereby inhibiting cancer cell proliferation[1][2][3]. Clinical development reached Phase 1 trials in patients with refractory solid tumors but was discontinued before further advancement[2][3][8].
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