Drug intelligence / Profile preview

standard-dose quadrivalent influenza vaccine

Development stage
Unknown
Lead developer
Sanofi Pasteur
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Standard-dose quadrivalent influenza vaccine (QIV-SD) refers to a class of seasonal vaccines designed to provide protection against four distinct influenza virus strains: two influenza A subtypes (typically H1N1 and H3N2) and two influenza B lineages (Victoria and Yamagata). The "standard-dose" terminology distinguishes these products from high-dose or adjuvanted formulations, as they typically contain 15 micrograms of hemagglutinin (HA) per strain, totaling 60 micrograms of HA per 0.5 mL dose. These vaccines are generally produced using egg-based or cell-based manufacturing technologies and are administered via intramuscular injection. They are indicated for the prevention of influenza-related illness in individuals across a wide age range, typically starting from 6 months of age, although specific age indications vary by brand.

Brand names
Fluzone QuadrivalentFluarix QuadrivalentFluLaval QuadrivalentAfluria QuadrivalentFlucelvax QuadrivalentAdimFlu-S
Other names
QIV-SDSD-QIVquadrivalent inactivated influenza vaccinestandard-dose QIVinfluenza virus vaccine, split virionquadrivalent influenza vaccine
02

Targets

HA (Hemagglutinin)

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