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Standard fluid management-Thomas Jefferson University-aneurysmal subarachnoid hemorrhage
- Development stage
- Unknown
- Lead developer
- Thomas Jefferson University
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Standard fluid management-Thomas Jefferson University-aneurysmal subarachnoid hemorrhage refers to the control arm protocol used in the HS3 (Hypertonic Saline in Aneurysmal SAH) Phase II clinical trial. This protocol represents the conventional isotonic fluid therapy (typically 0.9% sodium chloride) administered to patients following an aneurysmal subarachnoid hemorrhage (aSAH) to maintain euvolemia and prevent medical complications such as hyponatremia. In the context of the HS3 trial, this standard-of-care approach was used as a comparator to evaluate the safety and efficacy of 3% hypertonic saline in preventing cerebral vasospasm and improving clinical outcomes.
- Other names
- Standard fluid managementRoutine fluid management strategy
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