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Standard Preparation (University Hospital of Ferrara)

Development stage
Unknown
Lead developer
Azienda Ospedaliero-Universitaria di Ferrara
Modality
Small Molecules
Administration
Infiltration, Perineural
01

Overview

Standard Preparation (University Hospital of Ferrara) refers to the standard of care analgesic protocol used at the University Hospital of Ferrara for managing postoperative pain following neurosurgical procedures, such as supratentorial craniotomy. In the context of clinical research, this preparation consists of a troncular scalp blockade and local site infiltration. The procedure involves the administration of local anesthetics to block the sensory nerves of the scalp (including the supraorbital, supratrochlear, zygomaticotemporal, auriculotemporal, greater occipital, and lesser occipital nerves), thereby reducing the physiological stress response and providing regional anesthesia. This approach is typically compared against experimental interventions like sphenopalatine ganglion blocks to evaluate efficacy in reducing post-craniotomy headache and opioid consumption.

Other names
Troncular scalp blockadeLocal site infiltration
02

Targets

NaV (Voltage-gated sodium channels)

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