standardised 5-grass pollen allergen extract

Standardised 5-grass pollen allergen extract is a form of sublingual immunotherapy (SLIT) used to treat grass pollen-induced allergic rhinoconjunctivitis. It consists of extracts from five common types of grass pollens: Sweet Vernal (Anthoxanthum odoratum), Orchard (Dactylis glomerata), Perennial Rye (Lolium perenne), Timothy (Phleum pratense), and Kentucky Blue Grass (Poa pratensis). [1] Administered as drops under the tongue, the treatment works by gradually exposing the immune system to these allergens, which induces immunological tolerance, reduces the allergic response, and alleviates symptoms. [4, 7] The provided clinical trial context mentions ALK-Abelló as the sponsor, which is notable because ALK's primary grass pollen products (Grastek/Grazax) are based on a single grass, whereas the 5-grass mix is more commonly associated with Stallergenes Greer's products like Oralair (a tablet) and Staloral (drops). [3, 14, 20, 24] A recent Phase III trial by ALK, named RHAPSODY, has specifically evaluated a 5-grass-pollen SLIT drop formulation. [12]

Brand names

Staloral

Other names

5-grass mix SLIT-drops