Drug intelligence / Profile preview

staphylococcus + neisseria bacterial lysate

Development stage
Unknown
Lead developer
Qilu Pharmaceutical
Modality
Vaccines & Immunotherapeutics
Administration
Oral
01

Overview

Staphylococcus + neisseria bacterial lysate is an immunomodulatory preparation consisting of lysed components from *Staphylococcus* (specifically *Staphylococcus albus*) and *Neisseria* species. It is primarily used as an immunotherapy to prevent recurrent respiratory tract infections and manage chronic obstructive pulmonary disease (COPD). Administered orally, the lysate acts as an immunostimulant by activating innate immune pathways, such as Toll-like receptors (TLRs), which in turn enhances the production of secretory IgA (SIgA) in the respiratory mucosa. Research suggests it may also modulate the gut-airway microbiota axis and influence mitochondrial autophagy-related markers in lung tissues to reduce the frequency and severity of acute exacerbations in stable COPD patients.

Other names
Staphylococcus albus bacterial lysateNeisseria bacterial lysateBacterial lysate tablets
02

Targets

TLR2 (Toll-like Receptor 2)TLR4 (Toll-like receptor 4)

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