stavudine + lamivudine + nevirapine

Stavudine + lamivudine + nevirapine is a fixed-dose combination antiretroviral medication used in the treatment of HIV/AIDS. It contains three active ingredients: - Lamivudine and stavudine are nucleoside reverse transcriptase inhibitors (NRTIs) that inhibit HIV-1 reverse transcriptase by causing DNA chain termination after being phosphorylated to their active forms inside cells. - Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds directly to HIV-1 reverse transcriptase and blocks its RNA-dependent and DNA-dependent DNA polymerase activities by disrupting the enzyme's catalytic site. This combination reduces viral replication and increases CD4 cell counts. It is commonly used as first-line therapy in resource-limited settings and is included on the World Health Organization's List of Essential Medicines[1][2][5].

Brand names

TriomuneVirolansNevilastNevilast BabyNevilast JuniorNexvir SStavex LNTrivirEmduo N

Other names

lamivudine/nevirapine/stavudine