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STC-CI-01
- Development stage
- Preclinical
- Modality
- Recombinant Proteins and Enzymes
- Administration
- Intravenous, Subcutaneous, Intravitreal
01
Overview
STC-CI-01 appears to be a code name for an investigational drug or biologic related to stanniocalcin 1 (STC1), a glycoprotein hormone implicated in various physiological and pathological processes. Stanniocalcin 1 is known for its role in modulating mitochondrial function, calcium transport, and cellular metabolism. In cancer biology, STC1 has been identified as a phagocytosis checkpoint that enables tumor immune evasion by interacting with calreticulin (CRT) and inhibiting antigen-presenting cell activity. Targeting the STC1/CRT axis is being explored as a novel immunotherapeutic approach to overcome resistance to checkpoint blockade therapies in oncology. Additionally, stanniocalcin-1-based therapies have been investigated for ocular diseases such as retinal disorders.
02
Targets
STC1 (Stanniocalcin-1)
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