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STC042 is a preclinical-stage monoclonal antibody developed by Staidson Biopharmaceutical that targets thymic stromal lymphopoietin (TSLP). TSLP is an epithelial-derived cytokine that acts as an upstream master regulator of type 2 (T2) inflammation, playing a critical role in the pathogenesis of asthma. By binding to and neutralizing TSLP, STC042 is designed to prevent the activation of downstream inflammatory cells and cytokines, potentially offering a treatment option for a broad population of asthma patients, including those with non-eosinophilic profiles.
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