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STC2301 is a monoclonal antibody developed by Staidson Pharma (specifically Staidson Hongkong) that targets thymic stromal lymphopoietin (TSLP). TSLP is an epithelial-derived cytokine that plays a critical role in the initiation and persistence of type 2 inflammation, which is central to the pathogenesis of various allergic diseases. By neutralizing TSLP, STC2301 aims to modulate the inflammatory cascade upstream, potentially offering therapeutic benefits for patients with asthma and atopic dermatitis. As of early 2024, the drug is in Phase 1 clinical development.
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