Sterify Gel

Sterify Gel is a sterile, mucoadhesive bioactive hydrogel medical device developed by Sterify S.r.l. in collaboration with the University of Pavia for the treatment of peri-implantitis. The formulation is composed of polyvinyl polymers, hydroxytyrosol (a natural antioxidant), magnesium ascorbyl phosphate (a stable vitamin C derivative), and nisin (an antimicrobial peptide). It is designed to be applied into periodontal and peri-implant pockets following non-surgical debridement, where it adheres to gingival tissues and implant surfaces. This creates a protective physical barrier that prevents bacterial recolonization and supports the healing of inflammatory tissues. The gel is currently being evaluated in a randomized split-mouth clinical trial (NCT07088679) as an adjunct to standard mechanical therapy to improve clinical outcomes such as probing depth and bleeding on probing.

Brand names

Sterify Gel

Other names

Sterify Gel®