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Sterile water for injection is a sterile, nonpyrogenic, solute-free preparation of distilled water intended as a solvent or diluent vehicle for drugs or solutions suitable for parenteral administration. It contains no antimicrobial agents or added buffers and is used to dilute or dissolve medications prior to intravenous, intramuscular, or subcutaneous injection. The pH typically ranges from 5.0 to 7.0. It must be made approximately isotonic before direct intravenous administration; otherwise, it can cause hemolysis and other complications due to its hypotonicity[1][2][3][4][5][8]. Its primary mechanism is as a pharmaceutic aid (vehicle) rather than an active pharmacological agent.
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