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stinking hellebore extract
- Development stage
- Preclinical
- Lead developer
- Verein für Krebsforschung
- Modality
- Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
01
Overview
Stinking hellebore extract is a botanical preparation derived from the plant *Helleborus foetidus*. Developed by the Verein für Krebsforschung (Association for Cancer Research), the extract is being investigated for its potential antineoplastic properties. Research focuses on both fermented and unfermented versions of the extract, which have demonstrated in vitro cytotoxic activity against various cancer cell lines. While the exact molecular targets remain undefined, the extract is part of a broader research program into mistletoe and other botanical therapies for oncology. It is currently in the preclinical stage of development, with studies primarily focused on characterizing its cytotoxic profile in vitro.
- Other names
- Helleborus foetidus extractHelleborus foetidus
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