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stir-fried Chinese yam
- Development stage
- Unknown
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Stir-fried Chinese yam (Chao Shan Yao) is a traditional Chinese medicine (TCM) preparation of the rhizome of Dioscorea oppositifolia (syn. Dioscorea opposita). The preparation involves dry-frying or bran-frying (Fu Chao) the dried slices of Chinese yam until they turn pale yellow. This processing method is believed in TCM to enhance the herb's ability to tonify the Spleen and Stomach, harmonize the Middle Jiao, and stop diarrhea. It is commonly used to treat Spleen deficiency with chronic diarrhea, loose stools, poor appetite, and fatigue, as well as Kidney deficiency with leukorrhea or spermatorrhea. Chemically, it contains polysaccharides, mucilage, saponins (such as diosgenin), and starch, which contribute to its gastroprotective, immunomodulatory, and hypoglycemic properties.
- Other names
- bran-fried Chinese yamChao Shan Yaodry-fried Chinese yamdry-fried Dioscoreae RhizomaFu Chao Shan Yaoparched Chinese yamparched Rhizoma Dioscoreaestir-fried Shan Yao
02
Targets
ACE (Angiotensin Converting Enzyme)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)ESR1 (ERα)ESR2 (ERβ)MAPK3 (Mitogen-activated protein kinase 1)NFKB1 (NF-κB1)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)PRKAA1 (AMP-activated protein kinase alpha catalytic subunit isoform alpha-1)VEGFA (Vascular endothelial growth factor A)
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