Drug intelligence / Profile preview

stir-fried licorice root

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Stir-fried licorice root (traditionally known as *Zhi Gancao* or *Chao Gancao* in Traditional Chinese Medicine) is a processed herbal preparation derived from the dried roots and rhizomes of *Glycyrrhiza* species, primarily *Glycyrrhiza uralensis*, *Glycyrrhiza glabra*, or *Glycyrrhiza inflata*. The processing typically involves stir-frying the raw licorice root slices, often with honey (*Zhi Gancao*), which alters its chemical profile and therapeutic properties compared to the raw herb. This processing enhances its tonifying effects, making it warmer in nature and highly effective at replenishing Qi, strengthening the spleen and stomach, and regulating the pulse. Pharmacologically, stir-fried licorice root contains active triterpene saponins (such as glycyrrhizin and glycyrrhetinic acid) and flavonoids (such as liquiritin, liquiritigenin, isoliquiritin, and isoliquiritigenin). It is widely used to treat cardiac arrhythmias, palpitations, spleen deficiency, cough, and shortness of breath, and is a key component in classical TCM formulas like *Zhi Gancao Tang* and *Shaoyao Gancao Tang*.

Other names
Chao Gancaofried licorice rootGlycyrrhizae Radix et Rhizoma PraeparataGlycyrrhizae Radix et Rhizoma Praeparata Cum Mellehoney-fried licorice roothoney-roasted licorice rootMizhi Gancaoprepared licorice rootRadix Glycyrrhizae PreparataZhi GancaoZhi-gancaoZhigancao
02

Targets

HSD11B1 (11-beta-hydroxysteroid dehydrogenase type 1)HSD11B2 (11β-HSD2)AR (Adrenergic receptors)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ESR2 (ERβ)GR (Glucocorticoid receptor)HMGB1 (High mobility group protein B1)MR (Mineralocorticoid receptor)

Beyond the preview

Go deeper on stir-fried licorice root.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on stir-fried licorice root.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call