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STP2130

Development stage: Preclinical
Lead developer: ST Pharm
Modality: mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
Administration: Intramuscular

Overview

STP2130 is a preclinical-stage mRNA-based vaccine candidate developed by ST Pharm for the prevention of COVID-19. The vaccine utilizes ST Pharm's proprietary mRNA platform, which includes their 'SmartCap' technology for efficient mRNA capping and lipid nanoparticle (LNP) delivery systems. STP2130 is designed to encode the SARS-CoV-2 spike protein, triggering the host's immune system to produce protective antibodies and cellular immune responses. As of 2024, the program remains in the preclinical phase of development as part of ST Pharm's broader mRNA vaccine portfolio.

Targets

SARS-CoV-2 spike glycoprotein (Delta variant)

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