streptococcus pneumoniae type 9V capsular polysaccharide antigen

Streptococcus pneumoniae type 9V capsular polysaccharide antigen is a purified bacterial carbohydrate derived from the capsule of Streptococcus pneumoniae serotype 9V. It is used as an active component in both research and vaccine formulations to induce immunity against infections caused by this specific serotype. The mechanism of action involves stimulating the immune system to produce antibodies targeting the unique structure of the serotype 9V capsule, thereby providing protection against invasive diseases such as bacteremia and meningitis caused by Streptococcus pneumoniae. This antigen is included in several multivalent pneumococcal vaccines (such as PPV23, PCV10, PCV13, and others) that are indicated for prevention of invasive pneumococcal disease[2][6][7]. The primary developers and manufacturers include Pfizer (for purified bulk material), with inclusion in vaccines produced by companies such as Merck (Pneumovax23/PPV23), GlaxoSmithKline (Synflorix/PCV10), and Pfizer itself (Prevnar series)[1][2][4][6].

Other names

pneumococcal polysaccharide type 9vpneumococcal capsular polysaccharide type 9vpneumococcus serotype 9v antigen