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streptococcus thermophilus
- Development stage
- Unknown
- Lead developer
- LactoResearch
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
*Streptococcus thermophilus* is a Gram-positive, thermophilic lactic acid bacterium utilized as a live biotherapeutic product (probiotic). It is being investigated by LactoResearch sprl, specifically as a component of a 5-strain probiotic mixture for the treatment of lactose intolerance. The therapeutic effect is mediated by the bacterium's production of beta-galactosidase (lactase), an enzyme that hydrolyzes dietary lactose into glucose and galactose within the gastrointestinal tract, thereby alleviating symptoms such as bloating, flatulence, and diarrhea. A Phase 3 clinical trial in Belgian adults has evaluated its efficacy in improving lactose digestion, as measured by hydrogen breath testing and symptom logs.
- Brand names
- VSL#3VSL#3 DSVSL#3 Junior
- Other names
- S. thermophilus
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