Drug intelligence / Profile preview

streptococcus thermophilus KB27 + lactobacillus acidophilus KB31 + bifidobacterium longum KB35

Development stage
Unknown
Lead developer
Kibow Biotech
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Renadyl is a proprietary probiotic formulation developed by Kibow Biotech, consisting of three specific strains: *Streptococcus thermophilus* KB27, *Lactobacillus acidophilus* KB31, and *Bifidobacterium longum* KB35. It is designed to support kidney function by utilizing "enteric dialysis," a process where probiotic bacteria metabolize nitrogenous wastes (such as urea, uric acid, and creatinine) in the colon, thereby reducing the burden on impaired kidneys. It is primarily marketed as a dietary supplement for patients with chronic kidney disease (CKD) and has been evaluated in clinical trials for its ability to improve quality of life and reduce toxin levels in patients with renal failure. The formulation is also marketed for veterinary use under the brand name Azodyl for the management of azotemia in dogs and cats.

Brand names
RenadylAzodyl
Other names
Kibow BioticsEnteric Dialysis probiotic
02

Targets

PCS (p-Cresyl sulfate)IS (Indoxyl sulfate)

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