Drug intelligence / Profile preview

Stryphnodendron adstringens

Development stage
Preclinical
Modality
Small Molecules
Administration
Topical, Oral
01

Overview

Stryphnodendron adstringens is a tree native to Brazil and commonly known as "barbatimão." The stem bark is widely used in traditional medicine for its wound-healing, anti-inflammatory, antimicrobial, and astringent properties. Its pharmacological effects are attributed to high levels of tannins and polyphenols such as gallic acid and catechins (including epigallocatechin gallate), as well as other flavonoids like quercetin and kaempferol. Extracts from the bark have demonstrated immunomodulatory activity by reducing pro-inflammatory cytokine expression in vitro. Additional reported activities include antiprotozoal, hypoglycemic, antiviral effects, antioxidant properties, and potential anticancer activity. Formulations using the extract have been developed for topical use in wound healing[1][2][4][5][7].

Brand names
barbatimão
Other names
Stryphnodendron adstringensbarbatimãoAcacia adstringensMimosa barbadetimamMimosa virginalisStryphnodendron barbatimam

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