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STX-S

Development stage
Phase 1
Lead developer
Capricor Therapeutics
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

STX-S is an investigational exosome-based COVID-19 vaccine being developed by Capricor Therapeutics in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID). The vaccine platform utilizes proprietary exosomes engineered to express the SARS-CoV-2 spike (S) protein on their surface. By presenting the viral antigen in this manner, STX-S aims to stimulate a robust immune response. It is currently being evaluated in a Phase 1 dose-escalation study as a booster dose in healthy adults who have previously received primary COVID-19 vaccinations. This development program is supported by the U.S. government's Project NextGen initiative, which focuses on advancing next-generation vaccine technologies.

Other names
StealthX-spikeStealthX spikeexosome-mRNA vaccine (SARS-CoV-2)exosome COVID-19 mRNA vaccineexosome-based SARS-CoV-2 vaccine
02

Targets

SARS-CoV-2 spike

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