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Stylissa carteri primmorph extract is a natural product preparation derived from the 3D cell culture (primmorphs) of the marine sponge *Stylissa carteri*. Research indicates that this extract possesses antiproliferative properties, specifically inducing cell cycle arrest in HepG2 (hepatocellular carcinoma) cells. The use of primmorph culture systems is designed to provide a sustainable and controlled method for producing bioactive marine metabolites, overcoming the supply challenges associated with harvesting wild sponges. While the mesohyl of *S. carteri* lacks significant anticancer activity, the primmorph-derived extract shows potential as a source for novel chemotherapeutic agents.
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