Drug intelligence / Profile preview

succinic acid + inosine + taurine + methionine

Development stage
Unknown
Lead developer
The Michael J. Fox Foundation for Parkinson's Research
Modality
Small Molecules
Administration
Oral, Intravenous
01

Overview

This is a **combination drug** composed of **succinic acid**, **inosine**, **taurine**, and **methionine**, all of which act as metabolic agents with antioxidant and neuroprotective properties. Each ingredient in the combination has recognized roles in cellular metabolism and neuroprotection: - **Succinic acid** is a Krebs cycle intermediate involved in energy production and has antioxidant effects. - **Inosine** is a nucleoside that can support ATP synthesis and has neurotrophic properties. - **Taurine** is an amino acid implicated in membrane stabilization, osmoregulation, and neuroprotection. - **Methionine** is an essential amino acid involved in methylation reactions and cellular metabolism. Similar combinations with succinic acid, inosine, and other metabolic agents (though not taurine and methionine together) have been evaluated for neuroprotective effects, for example, in diabetic neuropathy and liver protection, chiefly due to antioxidant effects and mitochondrial support[1][3]. No unique brand name, code name, or proprietary clinical product is known for this precise four-compound combination.

02

Targets

SDH (Mitochondrial electron transport chain complex II)

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