Drug intelligence / Profile preview

sucralfate + oxetacaine

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Sucralfate + oxetacaine is a fixed-dose combination oral medication used primarily for the treatment of gastric and duodenal ulcers, heartburn, hyperacidity, gastritis, esophagitis, and related gastrointestinal conditions. **Mechanism of Action:** Sucralfate acts as a gastroprotective agent by forming a physical barrier over ulcerated or damaged mucosal tissue in the stomach or duodenum. This protective layer shields the tissue from further injury by gastric acid, pepsin, and bile salts, thereby promoting healing. Oxetacaine (also known as oxethazaine) is a potent local anesthetic that provides rapid pain relief by numbing the mucosal lining at the site of ulceration or inflammation through reversible inhibition of sensory nerve conduction. The combination thus offers both mucosal protection (sucralfate) and symptomatic pain relief (oxetacaine). **Primary Indications:** Treatment of peptic ulcers (gastric/duodenal), heartburn, hyperacidity/indigestion, gastritis (including NSAID-induced), esophagitis.

Brand names
Sucrafil OSucral-OMacralfate-OSft-OPepsigard-OSucraday-OUltracidOSucrace-OSucralcoat OKulfiOIfycid-OXRealfate-OZoxid-ONEUTER -OSUCRAFT O
Other names
sucralfate and oxetacaine suspension
02

Targets

NaV (Voltage-gated sodium channels)

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