Drug intelligence / Profile preview

sulfacetamide sodium + sulfur

Development stage
Unknown
Lead developer
Stiefel
Modality
Small Molecules
Administration
Topical
01

Overview

Sulfacetamide sodium + sulfur is a topical combination therapy used for the treatment of acne vulgaris, acne rosacea, and seborrheic dermatitis. It consists of sulfacetamide sodium, a sulfonamide antibiotic that inhibits bacterial growth by competing with para-aminobenzoic acid (PABA), and sulfur, which provides keratolytic and antifungal properties while inhibiting the growth of Propionibacterium acnes. This formulation is available in various topical forms such as cleansers, creams, and foams. Although widely used, many versions of this combination are marketed without formal FDA approval under the unapproved drugs category.

Brand names
PlexionAvarAvar-E GreenClenia PlusRosulaSSS Cleanser
Other names
sodium sulfacetamide + sulfursulfacetamide sodium and sulfur
02

Targets

DHPS (Dihydropteroate synthase)

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