sulfametrole

Sulfametrole is a sulfonamide antibiotic used primarily in combination with trimethoprim for the treatment of various bacterial infections. It belongs to the class of sulfonamides and acts as an antibacterial agent by inhibiting folic acid synthesis in bacteria. Sulfametrole is typically administered orally or intravenously and is available in some countries as a fixed-dose combination with trimethoprim. Its mechanism of action involves competitive inhibition of dihydropteroate synthase, an enzyme essential for bacterial folate synthesis, thereby blocking DNA and RNA production required for bacterial growth[1][2][3][4][5].

Other names

sulfametrolsulfametrolum4-amino-N-(4-methoxy-1,2,5-thiadiazol-3-yl)benzenesulfonamide